Gene
ambp
- ID
- ZDB-GENE-040426-1608
- Name
- alpha-1-microglobulin/bikunin precursor
- Symbol
- ambp Nomenclature History
- Previous Names
-
- ambpl (1)
- zgc:66321
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase inhibitor activity. Predicted to localize to cell surface and plasma membrane. Human ortholog(s) of this gene implicated in acute kidney failure and adult respiratory distress syndrome. Is expressed in liver and yolk syncytial layer. Orthologous to human AMBP (alpha-1-microglobulin/bikunin precursor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66321 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pickart et al., 2006
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
| Domain | IPR000566 | Lipocalin/cytosolic fatty-acid binding domain |
| Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
| Family | IPR002968 | Alpha-1-microglobulin |
| Family | IPR029856 | Protein AMBP |
| Homologous_superfamily | IPR012674 | Calycin |
| Homologous_superfamily | IPR036880 | Pancreatic trypsin inhibitor Kunitz domain superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-1-microglobulin | Calycin | Lipocalin/cytosolic fatty-acid binding domain | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | Protein AMBP | Proteinase inhibitor I2, Kunitz, conserved site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A7E2Q2
|
346 |
Interactions and Pathways
No data available
Plasmids
No data available