Gene
prpf31
- ID
- ZDB-GENE-040426-1561
- Name
- PRP31 pre-mRNA processing factor 31 homolog (yeast)
- Symbol
- prpf31 Nomenclature History
- Previous Names
-
- zgc:66177 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable U4atac snRNA binding activity. Acts upstream of or within mRNA splicing, via spliceosome and retina development in camera-type eye. Predicted to be located in nucleus. Predicted to be part of nucleus. Is expressed in head; retina; and retinal neural layer. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Orthologous to human PRPF31 (pre-mRNA processing factor 31).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66177 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 11 | Alliance | Retinitis pigmentosa 11 | 600138 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| retinitis pigmentosa | WT + MO1-prpf31 | standard conditions | (2) |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Nop, C-terminal domain | Nop domain | Nop domain superfamily | NOSIC | Prp31 C-terminal | U4/U6 small nuclear ribonucleoprotein Prp31 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SXM7
|
508 | ||||||
|
UniProtKB:B2GS36
|
508 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
prpf31-201
(1)
|
Ensembl | 1,867 nt | ||
| mRNA |
prpf31-202
(1)
|
Ensembl | 908 nt | ||
| mRNA |
prpf31-203
(1)
|
Ensembl | 1,542 nt |
Interactions and Pathways
No data available
Plasmids
No data available