Gene
pofut1
- ID
- ZDB-GENE-040303-2
- Name
- protein O-fucosyltransferase 1
- Symbol
- pofut1 Nomenclature History
- Previous Names
-
- zgc:110472
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have peptide-O-fucosyltransferase activity. Predicted to be involved in Notch signaling pathway and fucose metabolic process. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6906979 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dowling-Degos disease | Alliance | Dowling-Degos disease 2 | 615327 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GDP-fucose protein O-fucosyltransferase | GDP-fucose protein O-fucosyltransferase 1 |
|---|---|---|---|
|
UniProtKB:F1R676
|
395 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
pofut1-201
(1)
|
Havana | 1549 nt |
Interactions and Pathways
No data available
Plasmids
No data available