Gene
agps
- ID
- ZDB-GENE-031118-14
- Name
- alkylglycerone phosphate synthase
- Symbol
- agps Nomenclature History
- Previous Names
-
- fd16e06
- wu:fd16e06
- zgc:56718
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have FAD binding activity; alkylglycerone-phosphate synthase activity; and oxidoreductase activity. Predicted to be involved in ether lipid biosynthetic process and oxidation-reduction process. Predicted to localize to peroxisome. Human ortholog(s) of this gene implicated in rhizomelic chondrodysplasia punctata and rhizomelic chondrodysplasia punctata type 3. Orthologous to human AGPS (alkylglycerone phosphate synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56718 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| rhizomelic chondrodysplasia punctata type 3 | Alliance | Rhizomelic chondrodysplasia punctata, type 3 | 600121 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004113 | FAD-binding oxidoreductase/transferase, type 4, C-terminal |
| Domain | IPR006094 | FAD linked oxidase, N-terminal |
| Domain | IPR016166 | FAD-binding domain, PCMH-type |
| Family | IPR025650 | Alkyldihydroxyacetonephosphate synthase |
| Homologous_superfamily | IPR016164 | FAD-linked oxidase-like, C-terminal |
| Homologous_superfamily | IPR016167 | FAD-binding, type PCMH, subdomain 1 |
| Homologous_superfamily | IPR016169 | FAD-binding, type PCMH, subdomain 2 |
| Homologous_superfamily | IPR016171 | Vanillyl-alcohol oxidase, C-terminal subdomain 2 |
| Homologous_superfamily | IPR036318 | FAD-binding, type PCMH-like superfamily |
Domain Details Per Protein
| Protein | Length | Alkyldihydroxyacetonephosphate synthase | FAD-binding domain, PCMH-type | FAD-binding oxidoreductase/transferase, type 4, C-terminal | FAD-binding, type PCMH-like superfamily | FAD-binding, type PCMH, subdomain 1 | FAD-binding, type PCMH, subdomain 2 | FAD-linked oxidase-like, C-terminal | FAD linked oxidase, N-terminal | Vanillyl-alcohol oxidase, C-terminal subdomain 2 |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVJ9
|
629 | |||||||||
|
UniProtKB:A0A8M9PRZ0
|
602 |
Interactions and Pathways
No data available
Plasmids
No data available