Gene
tubb5
- ID
- ZDB-GENE-031110-4
- Name
- tubulin, beta 5
- Symbol
- tubb5 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Involved in fin regeneration. Predicted to localize to cytoplasm and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6. Is expressed in midbrain hindbrain boundary neural keel; nervous system; optic vesicle; and spinal cord neural tube. Orthologous to human TUBB (tubulin beta class I).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 13 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85895 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR013838 | Beta tubulin, autoregulation binding site |
Conserved_site | IPR017975 | Tubulin, conserved site |
Domain | IPR003008 | Tubulin/FtsZ, GTPase domain |
Domain | IPR018316 | Tubulin/FtsZ, 2-layer sandwich domain |
Family | IPR000217 | Tubulin |
Family | IPR002453 | Beta tubulin |
Homologous_superfamily | IPR008280 | Tubulin/FtsZ, C-terminal |
Homologous_superfamily | IPR023123 | Tubulin, C-terminal |
Homologous_superfamily | IPR036525 | Tubulin/FtsZ, GTPase domain superfamily |
Homologous_superfamily | IPR037103 | Tubulin/FtsZ-like, C-terminal domain |
Domain Details Per Protein
Protein | Length | Beta tubulin | Beta tubulin, autoregulation binding site | Tubulin | Tubulin, conserved site | Tubulin, C-terminal | Tubulin/FtsZ, 2-layer sandwich domain | Tubulin/FtsZ, C-terminal | Tubulin/FtsZ, GTPase domain | Tubulin/FtsZ, GTPase domain superfamily | Tubulin/FtsZ-like, C-terminal domain |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:Q6NW90
|
444 | ||||||||||
UniProtKB:A0A8M2BKU1
|
443 |
Interactions and Pathways
No data available
Plasmids
No data available