Gene

fam49a

ID

ZDB-GENE-031002-50

Name

family with sequence similarity 49 member A

Symbol

fam49a Nomenclature History

Previous Names

fam49ab (1)
sb:cb866
si:ch211-223o11.1
si:ch211-89p3.1
zgc:55309
znf395

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Involved in regulation of T cell differentiation and thymus development. Is expressed in several structures, including adaxial cell; digestive system; musculature system; sensory system; and trunk. Orthologous to human CYRIA (CYFIP related Rac1 interactor A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb866 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Li et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fam49a Human Ortholog

No data available

Associated With fam49a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009828	CYRIA/CYRIB, Rac1 binding domain
Family	IPR039789	CYFIP-related Rac1 interactor

Domain Details Per Protein

Protein	Length	CYFIP-related Rac1 interactor	CYRIA/CYRIB, Rac1 binding domain
UniProtKB:A0A0R4IMR9 InterPro	381
UniProtKB:A0A8M2B7R9 InterPro	324
UniProtKB:Q7ZW35 InterPro	323

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fam49a-201 (1) Ensembl	Havana	1851 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam49a-203 (1) Ensembl	Havana	1850 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	fam49a-206 (1) Ensembl	Havana	889 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	znf395-003 (1) Ensembl	Havana	302 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	znf395-004 (1) Ensembl	Havana	892 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	znf395-006 (1) Ensembl	Havana	738 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	znf395-007 (1) Ensembl	Havana	729 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations