ZFIN is now using GRCz12tu for Genomic Data
Gene
thoc2
- ID
- ZDB-GENE-030616-54
- Name
- THO complex 2
- Symbol
- thoc2 Nomenclature History
- Previous Names
-
- Tho2 (1)
- fb73e08
- fd21d11
- si:bz1o18.2
- wu:fb73e08
- wu:fd21d11
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in X-linked intellectual disability-short stature-overweight syndrome and arthrogryposis multiplex congenita. Orthologous to human THOC2 (THO complex subunit 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked intellectual disability-short stature-overweight syndrome | Alliance | Intellectual developmental disorder, X-linked syndromic, Kumar type | 300957 |
| Arthrogryposis multiplex congenita 7, X-linked | 301127 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | THO complex subunit 2 | THO complex subunit 2, N-terminal domain | THO complex, subunitTHOC2, C-terminal | THO complex, subunitTHOC2, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:F1R5B5 | InterPro | 1535 | ||||
| UniProtKB:F1QXF4 | InterPro | 1560 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
thoc2-202
(1)
|
Ensembl | 5,492 nt | ||
| mRNA |
thoc2-203
(1)
|
Ensembl | 5,457 nt | ||
| mRNA |
thoc2-204
(1)
|
Ensembl | 1,063 nt | ||
| ncRNA |
thoc2-001
(1)
|
Ensembl | 5,471 nt | ||
| ncRNA |
thoc2-002
(1)
|
Ensembl | 352 nt | ||
| ncRNA |
thoc2-005
(1)
|
Ensembl | 2,584 nt | ||
| ncRNA |
thoc2-006
(1)
|
Ensembl | 574 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers