Gene
pms1
- ID
- ZDB-GENE-030616-528
- Name
- PMS1 homolog 1, mismatch repair system component
- Symbol
- pms1 Nomenclature History
- Previous Names
-
- si:dz164h20.2
- si:dz72b14.2
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have ATPase activity. Predicted to be involved in mismatch repair. Predicted to localize to MutLalpha complex. Human ortholog(s) of this gene implicated in Lynch syndrome; dermatomyositis; and pancreatic ductal carcinoma. Orthologous to human PMS1 (PMS1 homolog 1, mismatch repair system component).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:66424 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR014762 | DNA mismatch repair, conserved site |
| Domain | IPR009071 | High mobility group box domain |
| Domain | IPR013507 | DNA mismatch repair protein, S5 domain 2-like |
| Family | IPR002099 | DNA mismatch repair protein MutL/Mlh/PMS |
| Family | IPR038973 | DNA mismatch repair protein MutL/Mlh/Pms-like |
| Homologous_superfamily | IPR014721 | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup |
| Homologous_superfamily | IPR020568 | Ribosomal protein uS5 domain 2-type superfamily |
| Homologous_superfamily | IPR036890 | Histidine kinase/HSP90-like ATPase superfamily |
| Homologous_superfamily | IPR036910 | High mobility group box domain superfamily |
Domain Details Per Protein
| Protein | Length | DNA mismatch repair, conserved site | DNA mismatch repair protein MutL/Mlh/PMS | DNA mismatch repair protein MutL/Mlh/Pms-like | DNA mismatch repair protein, S5 domain 2-like | High mobility group box domain | High mobility group box domain superfamily | Histidine kinase/HSP90-like ATPase superfamily | Ribosomal protein uS5 domain 2-type superfamily | Small ribosomal subunit protein uS5 domain 2-type fold, subgroup |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8JFR9
|
896 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA | ottdart00000001858 (1) | Havana | 117 nt | |
| mRNA | ottdart00000003997 (1) | Havana | 659 nt | |
| mRNA |
pms1-201
(1)
|
Havana | 2929 nt |
Interactions and Pathways
No data available
Plasmids
No data available