ZFIN is now using GRCz12tu for Genomic Data
Gene
dpy19l1l
- ID
- ZDB-GENE-030521-11
- Name
- dpy-19-like 1, like (H. sapiens)
- Symbol
- dpy19l1l Nomenclature History
- Previous Names
-
- KIAA0877-like (H. sapiens)
- kiaa0877l (1)
- sb:cb608
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable mannosyltransferase activity. Acts upstream of or within floor plate development; notochord morphogenesis; and protein C-linked glycosylation. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in floor plate; floor plate spinal cord region; neural rod; neural tube; and spinal cord neural tube. Used to study idiopathic scoliosis. Human ortholog(s) of this gene implicated in spermatogenic failure 9. Orthologous to several human genes including DPY19L1 (dpy-19 like C-mannosyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb608 (7 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| idiopathic scoliosis | AB + MO1-dpy19l1l | control | Tian et al., 2025 |
| idiopathic scoliosis | dpy19l1lzf4348/zf4348 (AB) | standard conditions | Tian et al., 2025 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR018732 | Dpy-19/Dpy-19-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Dpy-19/Dpy-19-like |
|---|---|---|---|
| UniProtKB:Q6DRN1 | InterPro | 730 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dpy19l1l-201
(1)
|
Ensembl | 2,339 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers