Gene
rrp8
- ID
- ZDB-GENE-030131-8898
- Name
- ribosomal RNA processing 8
- Symbol
- rrp8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have methylated histone binding activity. Predicted to be involved in cellular response to glucose starvation; chromatin silencing at rDNA; and regulation of transcription by glucose. Predicted to localize to chromatin silencing complex; nucleolus; and rDNA heterochromatin. Orthologous to human RRP8 (ribosomal RNA processing 8).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa14445 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Ribosomal RNA processing protein 8 | Ribosomal RNA-processing protein 8, N-terminal domain | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
---|---|---|---|---|
UniProtKB:F1R692
|
533 | |||
UniProtKB:A0A8M6YSH0
|
440 | |||
UniProtKB:B0R0L1
|
533 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
rrp8-203
(1)
|
Ensembl | 1,962 nt | ||
mRNA |
rrp8-204
(1)
|
Ensembl | 420 nt | ||
ncRNA |
si:ch211-149e23.3-002
(1)
|
Ensembl | 769 nt | ||
ncRNA |
si:ch211-149e23.3-003
(1)
|
Ensembl | 475 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-149E23 | ZFIN Curated Data | |
Contained in | BAC | CH211-152B13 | ZFIN Curated Data | |
Encodes | EST | fk33d07 |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_021472910 (1) | 1884 nt | ||
Genomic | GenBank:CR450848 (1) | 191457 nt | ||
Polypeptide | UniProtKB:B0R0L1 (2) | 533 aa |
- Giffen, K.P., Liu, H., Kramer, K.L., He, D.Z. (2019) Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Frontiers in neuroscience. 13:1117
- Fernandez, J.P., Moreno-Mateos, M.A., Gohr, A., Miao, L., Chan, S.H., Irimia, M., Giraldez, A.J. (2018) RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genetics. 14:e1007473
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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