Gene

drg1

ID

ZDB-GENE-030131-8767

Name

developmentally regulated GTP binding protein 1

Symbol

drg1 Nomenclature History

Previous Names

wu:fb06g12

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to localize to cytoplasm. Orthologous to human DRG1 (developmentally regulated GTP binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64124 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With drg1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Tan-Almurshedi syndrome	620641

Associated With drg1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR006074	GTP1/OBG, conserved site
Domain	IPR004095	TGS
Domain	IPR005225	Small GTP-binding domain
Domain	IPR006073	GTP binding domain
Domain	IPR031167	OBG-type guanine nucleotide-binding (G) domain
Domain	IPR031662	GTP binding protein, second domain
Family	IPR045001	Developmentally regulated GTP-binding protein
Homologous_superfamily	IPR012675	Beta-grasp domain superfamily
Homologous_superfamily	IPR012676	TGS-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase