Gene

nell2a

ID
ZDB-GENE-030131-7972
Name
neural EGFL like 2a
Symbol
nell2a Nomenclature History
Previous Names
  • nell2 (1)
  • wu:fj43h11
  • zgc:158375 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have heparin binding activity and protein kinase C binding activity. Predicted to localize to cytoplasm. Orthologous to human NELL2 (neural EGFL like 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Zhao et al., 2022
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nell2a Human Ortholog
No data available
Associated With nell2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001007 VWFC domain
Domain IPR001791 Laminin G domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR024731 EGF domain
Domain IPR048287 Thrombospondin-like, N-terminal domain
Domain IPR049883 NOTCH1 EGF-like calcium-binding domain
Family IPR051586 Protein kinase C-binding NELL
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily EGF domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Laminin G domain NOTCH1 EGF-like calcium-binding domain Protein kinase C-binding NELL Thrombospondin-like, N-terminal domain VWFC domain
UniProtKB:A1A5Y0 811
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nell2-201 (1) Ensembl 2,442 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations