Gene

itm2cb

ID
ZDB-GENE-030131-7806
Name
integral membrane protein 2Cb
Symbol
itm2cb Nomenclature History
Previous Names
  • itm2c
  • fj35c02
  • wu:fj35c02
  • zgc:66349
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable amyloid-beta binding activity. Predicted to be involved in negative regulation of amyloid precursor protein biosynthetic process. Predicted to be located in lysosomal membrane. Predicted to be active in Golgi apparatus and plasma membrane. Orthologous to human ITM2C (integral membrane protein 2C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa17500Allele with one point mutationUnknownSplice SiteENU
1 - 1 of 1
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Sequence Targeting Reagents
No data available
Human Disease
Associated With itm2cb Human Ortholog
No data available
Associated With itm2cb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007084 BRICHOS domain
Family IPR040145 Integral membrane protein 2
1 - 2 of 2
Domain Details Per Protein
Protein Length BRICHOS domain Integral membrane protein 2
UniProtKB:Q7SYK5 260
UniProtKB:A0A8M9QGD2 345
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA itm2cb-201 (1) Ensembl 1,857 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-195J11
EncodesESTfj35c02
EncodescDNAMGC:66349ZFIN Curated Data
EncodescDNAMGC:191768ZFIN Curated Data
1 - 4 of 4
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanITM2C2
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 8 of 8
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