Gene

lgals3a

ID
ZDB-GENE-030131-7667
Name
lectin, galactoside binding soluble 3a
Symbol
lgals3a Nomenclature History
Previous Names
  • lgals3
  • fb13c09
  • fk60g08
  • si:ch211-67f24.5
  • wu:fb13c09
  • wu:fk60g08 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have IgE binding activity and laminin binding activity. Predicted to be involved in several processes, including leukocyte chemotaxis; negative regulation of extrinsic apoptotic signaling pathway; and positive regulation of calcium ion import. Predicted to localize to several cellular components, including extracellular space; immunological synapse; and nucleus. Human ortholog(s) of this gene implicated in asthma. Orthologous to human LGALS3 (galectin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Wiweger et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lgals3a Human Ortholog
No data available
Associated With lgals3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001079 Galectin, carbohydrate recognition domain
Family IPR044156 Galectin-like
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Galectin, carbohydrate recognition domain Galectin-like
UniProtKB:A0A8M2B3V2 243
UniProtKB:A0A8N7UTJ9 368
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations