Gene
serbp1a
- ID
- ZDB-GENE-030131-7389
- Name
- SERPINE1 mRNA binding protein 1a
- Symbol
- serbp1a Nomenclature History
- Previous Names
-
- serbp1
- hm:zeh0245
- ndufb9
- wu:fa12d05
- wu:fb36e07
- wu:fc16f12
- wu:fj13e12
- zgc:55489
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable mRNA 3'-UTR binding activity. Predicted to act upstream of or within regulation of translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERBP1 (SERPINE1 mRNA binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55489 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hyaluronan/mRNA-binding protein | Intracellular hyaluronan-binding protein 4, N-terminal domain | RNA binding protein HABP4/SERBP1-like |
|---|---|---|---|---|
|
UniProtKB:F1Q5Q3
|
392 | |||
|
UniProtKB:Q802Z9
|
391 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
serbp1a-201
(1)
|
Ensembl | 2,344 nt | ||
| mRNA |
serbp1a-206
(1)
|
Ensembl | 2,270 nt | ||
| ncRNA |
serbp1a-002
(1)
|
Ensembl | 767 nt | ||
| ncRNA |
serbp1a-003
(1)
|
Ensembl | 767 nt | ||
| ncRNA |
serbp1a-004
(1)
|
Ensembl | 790 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-63D11 | ZFIN Curated Data | |
| Encodes | EST | fa12d05 | ||
| Encodes | EST | fb36e07 | ||
| Encodes | EST | fc16f12 | ||
| Encodes | EST | fj13e12 | ||
| Encodes | EST | zeh0245 | ||
| Encodes | cDNA | MGC:55489 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:85661 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:192406 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_214714 (1) | 2317 nt | ||
| Genomic | GenBank:BX323033 (1) | 171058 nt | ||
| Polypeptide | UniProtKB:F1Q5Q3 (1) | 392 aa |
- Farnsworth, D., Posner, M., Miller, A. (2021) Single cell transcriptomics of the developing zebrafish lens and identification of putative controllers of lens development. Experimental Eye Research. 206:108535
- Yan, Y., He, F., Li, Z., Xu, R., Li, T., Su, J., Liu, X., Zhao, M., Wu, W. (2018) The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 280:99-108
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Dong, X., Qiu, X., Meng, S., Xu, H., Wu, X., Yang, M. (2017) Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels. Chemosphere. 193:313-320
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Giousoh, A., Vaz, R., Bryson-Richardson, R.J., Whisstock, J.C., Verkade, H., Bird, P.I. (2015) Bone morphogenetic protein/retinoic acid inducible neural-specific protein (brinp) expression during Danio rerio development. Gene expression patterns : GEP. 18(1-2):37-43
- Cuello, S., Ximénez-Embún, P., Ruppen, I., Schonthaler, H.B., Ashman, K., Madrid, Y., Luque-Garcia, J.L., and Cámara, C. (2012) Analysis of protein expression in developmental toxicity induced by MeHg in zebrafish. The Analyst. 137(22):5302-5311
- Johnsen, H., and Andersen, O. (2012) Sex dimorphic expression of five dmrt genes identified in the Atlantic cod genome. The fish-specific dmrt2b diverged from dmrt2a before the fish whole-genome duplication. Gene. 505(2):221-232
- Valencia, C.A., Bailey, C., and Liu, R. (2007) Novel zebrafish caspase-3 substrates. Biochemical and Biophysical Research Communications. 361(2):311-316
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
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