Gene
myo1b
- ID
- ZDB-GENE-030131-695
- Name
- myosin IB
- Symbol
- myo1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization; actin filament-based movement; and endocytosis. Predicted to be part of myosin complex. Predicted to be active in several cellular components, including actin cytoskeleton; brush border; and microvillus. Is expressed in dorsolateral placode; lens; notochord; rhombomere; and somite. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Orthologous to several human genes including MYO1B (myosin IB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110446 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Diz-Munoz et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR001609 | Myosin head, motor domain-like |
| Domain | IPR010926 | Class I myosin tail homology domain |
| Domain | IPR036072 | Class I myosin, motor domain |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Class I myosin, motor domain | Class I myosin tail homology domain | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain-like | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3B2K3 | InterPro | 1138 | ||||||
| UniProtKB:A0A8M2BFG0 | InterPro | 1080 | ||||||
| UniProtKB:A0A8M2BFD8 | InterPro | 1109 | ||||||
| UniProtKB:A0A8M1RIU5 | InterPro | 1165 | ||||||
| UniProtKB:A0A8M3B5I5 | InterPro | 1138 | ||||||
| UniProtKB:A0A8M2BG11 | InterPro | 1167 | ||||||
| UniProtKB:A0A8M3AVX4 | InterPro | 1136 | ||||||
| UniProtKB:A0A8M2BFF2 | InterPro | 1109 | ||||||
| UniProtKB:A0A8M1QLB6 | InterPro | 1078 | ||||||
| UniProtKB:F1R617 | InterPro | 1107 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
myo1b-201
(1)
|
Ensembl | 772 nt | ||
| mRNA |
myo1b-203
(1)
|
Ensembl | 993 nt | ||
| mRNA |
myo1b-204
(1)
|
Ensembl | 5,429 nt | ||
| mRNA |
myo1b-206
(1)
|
Ensembl | 425 nt | ||
| mRNA |
myo1b-207
(1)
|
Ensembl | 501 nt | ||
| mRNA | ottdart00000002373 (1) | Havana | 3,355 nt | ||
| ncRNA |
myo1b-002
(1)
|
Ensembl | 777 nt | ||
| ncRNA |
myo1b-005
(1)
|
Ensembl | 643 nt |
Interactions and Pathways
No data available
Plasmids
No data available