ZFIN is now using GRCz12tu for Genomic Data
Gene
osbpl2b
- ID
- ZDB-GENE-030131-6138
- Name
- oxysterol binding protein-like 2b
- Symbol
- osbpl2b Nomenclature History
- Previous Names
-
- osbpl2
- wu:fi36a04
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cholesterol binding activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Is expressed in several structures, including blastodisc; digestive system; nervous system; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67 and dyschromatosis, ichthyosis, deafness, and atopic disease. Orthologous to human OSBPL2 (oxysterol binding protein like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153548 (11 images)
- MGC:55948 (14 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 67 | Alliance | Deafness, autosomal dominant 67 | 616340 |
| dyschromatosis, ichthyosis, deafness, and atopic disease | Alliance | Dyschromatosis, ichthyosis, deafness, and atopic disease | 621400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Oxysterol-binding protein | Oxysterol-binding protein, conserved site | Oxysterol-binding protein superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q7ZVL1 | InterPro | 472 | |||
| UniProtKB:A0A8M2B8V1 | InterPro | 473 | |||
| UniProtKB:A0AC58IJ35 | InterPro | 472 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
osbpl2b-201
(1)
|
Ensembl | 2,288 nt | ||
| mRNA |
osbpl2b-202
(1)
|
Ensembl | 685 nt | ||
| mRNA |
osbpl2b-203
(1)
|
Ensembl | 755 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers