ZFIN is now using GRCz12tu for Genomic Data
Gene
hgs
- ID
- ZDB-GENE-030131-6107
- Name
- hepatocyte growth factor-regulated tyrosine kinase substrate
- Symbol
- hgs Nomenclature History
- Previous Names
-
- fi34f05
- wu:fi34f05
- zgc:63492 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metal ion binding activity; phosphatidylinositol binding activity; and ubiquitin binding activity. Predicted to be located in early endosome membrane and multivesicular body membrane. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63492 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003903 | Ubiquitin interacting motif |
| Domain | IPR000306 | FYVE zinc finger |
| Domain | IPR002014 | VHS domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR024641 | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain |
| Family | IPR017073 | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 |
| Homologous_superfamily | IPR008942 | ENTH/VHS |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | ENTH/VHS | FYVE zinc finger | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 | Ubiquitin interacting motif | VHS domain | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PSI2 | InterPro | 776 | |||||||||
| UniProtKB:A0A8M2BBJ6 | InterPro | 773 | |||||||||
| UniProtKB:A0A8M9PK93 | InterPro | 771 | |||||||||
| UniProtKB:A0A8M9PSI7 | InterPro | 768 | |||||||||
| UniProtKB:E9QCS7 | InterPro | 757 | |||||||||
| UniProtKB:A0A8M9PW14 | InterPro | 761 | |||||||||
| UniProtKB:A0A8M9PEL3 | InterPro | 767 | |||||||||
| UniProtKB:A0A8M9P4S8 | InterPro | 762 | |||||||||
| UniProtKB:A0A8M9PVZ9 | InterPro | 777 | |||||||||
| UniProtKB:A0AB32TBW5 | InterPro | 772 | |||||||||
| UniProtKB:A0AB32TDF4 | InterPro | 767 | |||||||||
| UniProtKB:A0AB32TEX5 | InterPro | 763 | |||||||||
| UniProtKB:A0AB32TF21 | InterPro | 758 | |||||||||
| UniProtKB:A0AB32TGM9 | InterPro | 764 | |||||||||
| UniProtKB:A0AC58IF69 | InterPro | 766 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers