Gene

trmt5

ID
ZDB-GENE-030131-5978
Name
tRNA methyltransferase 5
Symbol
trmt5 Nomenclature History
Previous Names
  • wu:fi28b08
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have tRNA (guanine-N1-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to localize to mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 26. Orthologous to human TRMT5 (tRNA methyltransferase 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trmt5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 26 Alliance Peripheral neuropathy with variable spasticity, exercise intolerance, and developmental delay 616539
Associated With trmt5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type
Family IPR025792 tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Domain Details Per Protein
Protein Length S-adenosyl-L-methionine-dependent methyltransferase superfamily SAM-dependent methyltransferase TRM5/TYW2-type tRNA (guanine(37)-N(1))-methyltransferase, eukaryotic
UniProtKB:B8A5G9
UniProtKB:A0A8M9QFG2 245
UniProtKB:A0A8M3AZ45 449
UniProtKB:A0A8M3B822 245
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations