Gene

cul5a

ID

ZDB-GENE-030131-5426

Name

cullin 5a

Symbol

cul5a Nomenclature History

Previous Names

cul5
wu:fd17d09
wu:fi20h12
xx:11fd17d09
zgc:66185

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to Cul5-RING ubiquitin ligase complex and SCF ubiquitin ligase complex. Orthologous to human CUL5 (cullin 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66185 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cul5a Human Ortholog

No data available

Associated With cul5a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR016157	Cullin, conserved site
Domain	IPR001373	Cullin, N-terminal
Domain	IPR016158	Cullin homology domain
Domain	IPR019559	Cullin protein, neddylation domain
Family	IPR045093	Cullin
Homologous_superfamily	IPR016159	Cullin repeat-like-containing domain superfamily
Homologous_superfamily	IPR036317	Cullin homology domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily