Gene

e2f6

ID

ZDB-GENE-030131-513

Name

E2F transcription factor 6

Symbol

e2f6 Nomenclature History

Previous Names

fb34f06
si:ch211-195d17.2
THAP-E2F6 fusion gene (1)
wu:fb34f06
zgc:136607

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Predicted to localize to RNA polymerase II transcription factor complex.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu1069 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With e2f6 Human Ortholog

No data available

Associated With e2f6 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Domain	IPR006612	THAP-type zinc finger
Domain	IPR032198	E2F transcription factor, CC-MB domain
Family	IPR015633	E2F Family
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily
Homologous_superfamily	IPR037241	E2F-DP heterodimerization region
Homologous_superfamily	IPR038441	THAP-type zinc finger superfamily

Domain Details Per Protein

Protein	Length	E2F/DP family, winged-helix DNA-binding domain	E2F-DP heterodimerization region	E2F Family	E2F transcription factor, CC-MB domain	THAP-type zinc finger	THAP-type zinc finger superfamily	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:Q5TZC4 InterPro	406
UniProtKB:A0A8M1N779 InterPro	405

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:ch211-195d17.2-202 (1) Ensembl	Havana	1412 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	si:ch211-195d17.2-203 (1) Ensembl	Havana	1583 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations