Gene

pde4cb

ID

ZDB-GENE-030131-4075

Name

phosphodiesterase 4C, cAMP-specific b

Symbol

pde4cb Nomenclature History

Previous Names

fc68c05
si:ch211-255d18.1
wu:fc68c05

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have 3',5'-cyclic-AMP phosphodiesterase activity. Predicted to be involved in signal transduction. Orthologous to human PDE4C (phosphodiesterase 4C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

eu1105 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pde4cb Human Ortholog

No data available

Associated With pde4cb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site
Domain	IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain
Domain	IPR003607	HD/PDEase domain
Domain	IPR040844	Phosphodiesterase 4 upstream conserved regions (UCR)
Family	IPR023088	3'5'-cyclic nucleotide phosphodiesterase
Homologous_superfamily	IPR036971	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	3'5'-cyclic nucleotide phosphodiesterase	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	3'5'-cyclic nucleotide phosphodiesterase, conserved site	HD/PDEase domain	Phosphodiesterase 4 upstream conserved regions (UCR)
UniProtKB:A0A8M9QHV8 InterPro	693
UniProtKB:A0A8M9Q7G4 InterPro	670
UniProtKB:A0A0R4IMH2 InterPro	680
UniProtKB:A0A8M9QLT1 InterPro	721

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pde4cb-201 (1) Ensembl	Havana	2548 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pde4cb-202 (1) Ensembl	Havana	2966 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations