Gene

arhgap27

ID

ZDB-GENE-030131-3922

Name

Rho GTPase activating protein 27

Symbol

arhgap27 Nomenclature History

Previous Names

fc59a09
wu:fc59a09

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have GTPase activator activity. Predicted to be involved in regulation of GTPase activity. Predicted to localize to cytoplasm. Is expressed in ectoderm. Orthologous to human ARHGAP27 (Rho GTPase activating protein 27).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Kimelman et al., 2017

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap27 Human Ortholog

No data available

Associated With arhgap27 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001202	WW domain
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR036020	WW domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily

Domain Details Per Protein

Protein	Length	PH-like domain superfamily	Pleckstrin homology domain	Rho GTPase-activating protein domain	Rho GTPase activation protein	SH3 domain	SH3-like domain superfamily	WW domain	WW domain superfamily
UniProtKB:A0A8M2B2D3 InterPro	999
UniProtKB:A0A8M3B778 InterPro	780
UniProtKB:A0A8M1RHJ9 InterPro	763
UniProtKB:E7FCI7 InterPro	970
UniProtKB:A0A8M9PWQ0 InterPro	946
UniProtKB:A0A8M9QIZ3 InterPro	975

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	arhgap27-201 (1) Ensembl	Havana	4401 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations