Gene

thoc5

ID
ZDB-GENE-030131-3789
Name
THO complex 5
Symbol
thoc5 Nomenclature History
Previous Names
  • fc54b09
  • wu:fc54b09
  • zgc:56190
  • zgc:76912
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus and positive regulation of DNA-templated transcription, elongation. Predicted to act upstream of or within RNA processing; cell differentiation; and mRNA transport. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human THOC5 (THO complex subunit 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la023359TgTransgenic insertionUnknownUnknownDNA
sa37987Allele with one point mutationUnknownSplice SiteENU
sa37988Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With thoc5 Human Ortholog
No data available
Associated With thoc5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019163 THO complex, subunit 5
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Domain Details Per Protein
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 25
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA thoc5-201 (1) Ensembl 2,348 nt
mRNA thoc5-202 (1) Ensembl 677 nt
mRNA thoc5-203 (1) Ensembl 872 nt
mRNA thoc5-204 (1) Ensembl 4,188 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-43O9ZFIN Curated Data
EncodesESTfc54b09
EncodescDNAMGC:56190ZFIN Curated Data
EncodescDNAMGC:76912ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTHOC522
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseThoc511
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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