Gene

dclre1a

ID
ZDB-GENE-050522-124
Name
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)
Symbol
dclre1a Nomenclature History
Previous Names
  • fc49f05
  • im:7145629
  • wu:fc49f05
  • zgc:109999
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have 5'-3' exodeoxyribonuclease activity and damaged DNA binding activity. Predicted to be involved in double-strand break repair via nonhomologous end joining; interstrand cross-link repair; and protection from non-homologous end joining at telomere. Predicted to localize to nuclear chromosome, telomeric region. Orthologous to human DCLRE1A (DNA cross-link repair 1A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dclre1a Human Ortholog
No data available
Associated With dclre1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001279 Metallo-beta-lactamase
Domain IPR006642 Rad18, zinc finger UBZ4-type
Domain IPR011084 DNA repair metallo-beta-lactamase
Homologous_superfamily IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Domain Details Per Protein
Protein Length DNA repair metallo-beta-lactamase Metallo-beta-lactamase Rad18, zinc finger UBZ4-type Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
UniProtKB:E7F457 926
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA dclre1a-201 (1) Havana 3316 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations