Gene
sgcd
- ID
- ZDB-GENE-030131-3684
- Name
- sarcoglycan, delta (dystrophin-associated glycoprotein)
- Symbol
- sgcd Nomenclature History
- Previous Names
-
- wu:fc49e11
- zgc:110649
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Involved in several processes, including heart contraction; somatic muscle development; and swim bladder inflation. Localizes to sarcolemma. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2F; dilated cardiomyopathy 1L; and muscular dystrophy. Is expressed in several structures, including brain; cardiovascular system; musculature system; retina; and swim bladder. Orthologous to human SGCD (sarcoglycan delta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Vogel et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive limb-girdle muscular dystrophy type 2F | Alliance | Muscular dystrophy, limb-girdle, autosomal recessive 6 | 601287 |
| dilated cardiomyopathy 1L | Alliance | Cardiomyopathy, dilated, 1L | 606685 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sarcoglycan complex subunit protein | Sarcoglycan gamma/delta/zeta |
|---|---|---|---|
|
UniProtKB:A0A0R4IBS6
|
292 | ||
|
UniProtKB:A0A8M3AU43
|
288 |
Interactions and Pathways
No data available
Plasmids
No data available