Gene
rgs6
- ID
- ZDB-GENE-030131-31
- Name
- regulator of G protein signaling 6
- Symbol
- rgs6 Nomenclature History
- Previous Names
-
- hm:zeh0300
- si:ch211-268e23.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within intracellular signal transduction; negative regulation of signal transduction; and regulation of G protein-coupled receptor signaling pathway. Predicted to be active in cytoplasm and neuron projection. Is expressed in nervous system and trigeminal placode. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human RGS6 (regulator of G protein signaling 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2005
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu1068 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Thyme et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000591 | DEP domain |
| Domain | IPR015898 | G-protein gamma-like domain |
| Domain | IPR016137 | RGS domain |
| Domain | IPR037956 | RGS6, RGS domain |
| Domain | IPR040759 | Regulator of G-protein signalling, DHEX domain |
| Family | IPR047016 | Regulator of G protein signaling 6/7/9/11 |
| Homologous_superfamily | IPR036284 | G-protein gamma-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
| Homologous_superfamily | IPR047017 | Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily |
Domain Details Per Protein
| Protein | Length | DEP domain | G-protein gamma-like domain | G-protein gamma-like domain superfamily | Regulator of G protein signaling 6/7/9/11 | Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily | Regulator of G-protein signalling, DHEX domain | RGS6, RGS domain | RGS domain | RGS domain superfamily | RGS, subdomain 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q38JL1
|
489 |
Interactions and Pathways
No data available
Plasmids
No data available