Gene

hcfc1b

ID
ZDB-GENE-030131-2411
Name
host cell factor C1b
Symbol
hcfc1b Nomenclature History
Previous Names
  • fc07b09
  • fe17f08
  • wu:fc07b09
  • wu:fe17f08
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to contribute to histone acetyltransferase activity. Involved in chondrocyte differentiation and embryonic viscerocranium morphogenesis. Predicted to localize to Ada2/Gcn5/Ada3 transcription activator complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human HCFC1 (host cell factor C1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hcfc1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
methylmalonic acidemia and homocysteinemia cblX type Alliance Methylmalonic aciduria and homocysteinemia, cblX type 309541
Associated With hcfc1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Family IPR043536 Host cell factor
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR015915 Kelch-type beta propeller
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Repeat IPR006652 Kelch repeat type 1
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Host cell factor Immunoglobulin-like fold Kelch repeat type 1 Kelch-type beta propeller
UniProtKB:A0A8M2BE35 1990
UniProtKB:A0A8M9Q3I3 1958
UniProtKB:A0A8M9PQY4 1993
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations