Gene

wdhd1

ID

ZDB-GENE-030131-1665

Name

WD repeat and HMG-box DNA binding protein 1

Symbol

wdhd1 Nomenclature History

Previous Names

AND-1 (1)
wu:fa11f10
wu:fb77d12
zgc:92585

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to enable chromatin binding activity. Predicted to be involved in DNA repair; DNA-templated DNA replication; and mitotic cell cycle. Predicted to be located in nucleus. Predicted to be active in nuclear replication fork. Is expressed in blood; brain; proliferative region; and spinal cord. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Orthologous to human WDHD1 (WD repeat and HMG-box DNA binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92585 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdhd1 Human Ortholog

No data available

Associated With wdhd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR009071	High mobility group box domain
Domain	IPR022100	WDHD1/CFT4, second beta-propeller
Domain	IPR048591	WDHD1/CFT4, helical bundle
Domain	IPR055339	WD repeat and HMG-box DNA-binding protein 1, HMG-box
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Homologous_superfamily	IPR036910	High mobility group box domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Additional Resources	Length	High mobility group box domain	High mobility group box domain superfamily	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily	WDHD1/CFT4, helical bundle	WDHD1/CFT4, second beta-propeller	WD repeat and HMG-box DNA-binding protein 1, HMG-box
UniProtKB:A0A0R4J7S6	InterPro	1112
UniProtKB:A0A8M9PNN9	InterPro	1113

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	wdhd1-203 (1) Ensembl	Ensembl	1,466 nt	Select Tool ZFIN BLAST
antisense	ottdart00000055329 (1) Ensembl	Ensembl	252 nt	Select Tool ZFIN BLAST
antisense	ottdart00000055330 (1) Ensembl	Ensembl	351 nt	Select Tool ZFIN BLAST
antisense	ottdart00000055332 (1) Ensembl	Ensembl	925 nt	Select Tool ZFIN BLAST
antisense	ottdart00000055333 (1) Ensembl	Ensembl	804 nt	Select Tool ZFIN BLAST
mRNA	wdhd1-201 (1) Ensembl	Ensembl	4,865 nt	Select Tool ZFIN BLAST
mRNA	wdhd1-202 (1) Ensembl	Ensembl	3,665 nt	Select Tool ZFIN BLAST
mRNA	wdhd1-204 (1) Ensembl	Ensembl	499 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations