Gene
hip1
- ID
- ZDB-GENE-010328-15
- Name
- huntingtin interacting protein 1
- Symbol
- hip1 Nomenclature History
- Previous Names
-
- fb98d04
- wu:fb98d04
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; clathrin binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in chordate embryonic development and response to yeast. Predicted to localize to actin cortical patch and intracellular membrane-bounded organelle. Orthologous to human HIP1 (huntingtin interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Komoike et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Targeting Reagent | Created Alleles | Citations |
---|---|---|
MO1-hip1 | N/A | Komoike et al., 2010 |
MO2-hip1 | N/A | Komoike et al., 2010 |
1 - 2 of 2
Show
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | AP180 N-terminal homology (ANTH) domain | ENTH domain | ENTH/VHS | Huntingtin-interacting protein 1, clathrin-binding domain | I/LWEQ domain | I/LWEQ domain superfamily | Sla2 family |
---|---|---|---|---|---|---|---|---|
UniProtKB:F1R6L2
|
1048 | |||||||
UniProtKB:A0A8M3ASL4
|
1014 | |||||||
UniProtKB:C9K4U5
|
1046 | |||||||
UniProtKB:A0A8M2B3I8
|
1014 |
1 - 4 of 4
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-214G1 | ZFIN Curated Data | |
Contained in | BAC | DKEY-264N17 | ||
Encodes | EST | fb98d04 |
1 - 3 of 3
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001166205 (1) | 3790 nt | ||
Genomic | GenBank:CR513790 (1) | 157412 nt | ||
Polypeptide | UniProtKB:F1R6L2 (1) | 1048 aa |
- Lu, J., Liu, L., Zheng, M., Li, X., Wu, A., Wu, Q., Liao, C., Zou, J., Song, H. (2018) MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 function. Oncogene. 37:3864-3878
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Wang, Y.C., Lin, C., Chuang, M.T., Hsieh, W.P., Lan, C.Y., Chuang, Y.J., and Chen, B.S. (2013) Interspecies protein-protein interaction network construction for characterization of host-pathogen interactions: a Candida albicans-zebrafish interaction study. BMC systems biology. 7:79
- Komoike, Y., Fujii, K., Nishimura, A., Hiraki, Y., Hayashidani, M., Shimojima, K., Nishizawa, T., Higashi, K., Yasukawa, K., Saitsu, H., Miyake, N., Mizuguchi, T., Matsumoto, N., Osawa, M., Kohno, Y., Higashinakagawa, T., and Yamamoto, T. (2010) Zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly. Genesis (New York, N.Y. : 2000). 48(4):233-243
- Kollmar, R., Nakamura, S.K., Kappler, J.A., and Hudspeth, A.J. (2001) Expression and phylogeny of claudins in vertebrate primordia. Proceedings of the National Academy of Sciences of the United States of America. 98(18):10196-10201
1 - 5 of 5
Show