Gene
papss2b
- ID
- ZDB-GENE-010323-5
- Name
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2b
- Symbol
- papss2b Nomenclature History
- Previous Names
-
- papss2
- id:ibd2761
- sb:cb868
- wu:fb12e05
- zgc:55851
- zgc:85655
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have sulfate adenylyltransferase (ATP) activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Is expressed in several structures, including digestive system; mesoderm; pectoral fin; pectoral fin bud; and sensory system. Orthologous to human PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb868 (24 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondyloepimetaphyseal dysplasia, Pakistani type | Alliance | Brachyolmia 4 with mild epiphyseal and metaphyseal changes | 612847 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR024951 | Sulphate adenylyltransferase catalytic domain |
| Domain | IPR025980 | ATP-sulfurylase PUA-like domain |
| Family | IPR002650 | Sulphate adenylyltransferase |
| Family | IPR002891 | Adenylyl-sulfate kinase |
| Homologous_superfamily | IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
| Homologous_superfamily | IPR015947 | PUA-like superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | Adenylyl-sulfate kinase | ATP-sulfurylase PUA-like domain | P-loop containing nucleoside triphosphate hydrolase | PUA-like superfamily | Rossmann-like alpha/beta/alpha sandwich fold | Sulphate adenylyltransferase | Sulphate adenylyltransferase catalytic domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q802U9
|
614 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
papss2b-201
(1)
|
Havana | 2674 nt |
Interactions and Pathways
No data available
Plasmids
No data available