Gene

cdk1

ID
ZDB-GENE-010320-1
Name
cyclin dependent kinase 1
Symbol
cdk1 Nomenclature History
Previous Names
  • cdc2
  • wu:fc30e01
  • zgc:92032
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have RNA polymerase II CTD heptapeptide repeat kinase activity and cyclin-dependent protein serine/threonine kinase activity. Involved in regulation of mitotic cell cycle, embryonic. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Is expressed in eye. Orthologous to human CDK1 (cyclin dependent kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 14 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdk1 Human Ortholog
No data available
Associated With cdk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q7T3L7 302
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations