PUBLICATION
Cloning and characterization of a 70 kd heat shock cognate (hsc70) gene from the zebrafish (Danio rerio)
- Authors
- Graser, R.T., Malnar-Dragojevic, D., and Vincek, V.
- ID
- ZDB-PUB-970812-5
- Date
- 1996
- Source
- Genetica 98(3): 273-276 (Journal)
- Registered Authors
- Vincek, V.
- Keywords
- hsc70; zebrafish
- MeSH Terms
-
- Animals
- Carrier Proteins/genetics*
- Cloning, Molecular
- HSC70 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins/genetics*
- Molecular Sequence Data
- Phylogeny
- Zebrafish/genetics*
- Zebrafish Proteins
- PubMed
- 9204550 Full text @ Genetica
Citation
Graser, R.T., Malnar-Dragojevic, D., and Vincek, V. (1996) Cloning and characterization of a 70 kd heat shock cognate (hsc70) gene from the zebrafish (Danio rerio). Genetica. 98(3):273-276.
Abstract
The heat shock 70 family of proteins is one of the most highly conserved among all species. The genes encoding these proteins have been cloned and sequenced from bacterial species to humans with a high degree of homology preserved throughout evolution. Here we describe the cloning and characterization of a cDNA encoding a 70 kd heat shock cognate (hsc70) gene from the zebrafish (Danio rerio). A high degree of conservation is observed among hsc70 genes of other species as shown by phylogenetic analysis. The characterization of a hsc70 gene in the zebrafish provides a marker for studying the role of a constitutively expressed member of the hsp70 family in an important developmental and evolutionary model system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping