PUBLICATION
Thyroid hormones in growth and development of fish
- Authors
- Power, D.M., Llewellyn, L., Faustino, M., Nowell, M.A., Bjornsson, B.T., Einarsdottir, I.E., Canario, A.V., and Sweeney, G.E.
- ID
- ZDB-PUB-011214-1
- Date
- 2001
- Source
- Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 130(4): 447-459 (Journal)
- Registered Authors
- Keywords
- development, embryogenesis, metamorphosis, teleost fish, thyroid hormones, thyroid hormone receptors, ring deiodinase activities, whole-body concentrations, Salmo gairdnerii irideus, iodothyronine outer ring, larval striped bass, bream Sparus aurata, yolk-sac larvae, rainbow trout, chum salmon, sea bream
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Embryo, Nonmammalian/physiology*
- Fishes/growth & development*
- Fishes/physiology
- Larva/physiology
- Metamorphosis, Biological/physiology
- Molecular Sequence Data
- Receptors, Thyroid Hormone/genetics
- Receptors, Thyroid Hormone/physiology
- Sequence Alignment
- Thyroxine/metabolism
- Thyroxine/physiology*
- Triiodothyronine/metabolism
- Triiodothyronine/physiology*
- PubMed
- 11738632 Full text @ Comp. Biochem. Physiol. C Toxicol. Pharmacol.
Citation
Power, D.M., Llewellyn, L., Faustino, M., Nowell, M.A., Bjornsson, B.T., Einarsdottir, I.E., Canario, A.V., and Sweeney, G.E. (2001) Thyroid hormones in growth and development of fish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 130(4):447-459.
Abstract
The thyroid hormones (THs), thyroxine (T(4)) and triiodothyronine (T(3)) are products of the thyroid gland in all vertebrates. Their role in early development and metamorphosis is well established in mammals and amphibians, respectively, and recently several studies in fish have highlighted the importance of THs during flatfish metamorphosis. THs are present in high quantities in fish eggs and are presumably of maternal origin. During embryogenesis the concentration of T(4) and T(3) in the eggs decrease until endogenous production starts. Thyroid hormone receptors (TR) have been isolated from several teleosts and in common with tetrapods two receptor isoforms have been identified, TRalpha and TRbeta. Both the receptors are expressed in early embryos and larvae of the Japanese flounder (Paralichthys olivaceus), zebrafish (Danio rerio) and seabream (Sparus aurata) although a different temporal pattern is apparent. The role of THs and TRs in fish embryogenesis, larval development and during metamorphosis will be discussed.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping