- Title
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Zebrafish Avatars of rectal cancer patients validate the radiosensitive effect of metformin
- Authors
- Costa, B., Fernandez, L.M., Parés, O., Rio-Tinto, R., Santiago, I., Castillo-Martin, M., Parvaiz, A., Fior, R.
- Source
- Full text @ Front Oncol
Human CRC cells HCT116 were injected into the PVS of 2dpf zebrafish embryos. At 1dpi xenografts were submitted to 5FU chemotherapy |
Human CRC cells Hke3 were injected into the PVS of 2dpf zebrafish embryos. At 1dpi xenografts were submitted to 5FU chemotherapy |
zAvatars were generated from rectum cancer surgical resected samples. One day after injection zAvatars were submitted to 25Gy radiation dose |
zAvatars were generated from naive rectal cancer biopsies. One day after injection zAvatars were submitted to 25Gy radiation dose |