FIGURE SUMMARY
Title

Channa Striatus Protects Against PTZ-Induced Seizures in LPS Pre-conditioned Zebrafish Model

Authors
Lee, V.L.L., Norazit, A., Noor, S.M., Shaikh, M.F.
Source
Full text @ Front Pharmacol
FIGURE 1

(A) Representative swimming pattern of zebrafish in each group. (B) Mean total distance travelled (cm) by zebrafish in each group. The p-values ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05 were regarded as statistically significant for the treatment groups compared to the negative control (LPS + PTZ). The p-values ####p < 0.0001, ###p < 0.001, ##p < 0.01 and #p < 0.05 was regarded as statistically significant for the per se groups compared to the control.
FIGURE 2

(A) Seizure score 4 onset time for each group. (B) Mean seizure scores for each group. The p-values ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05 were regarded as statistically significant for the treatment groups compared to the negative control (LPS + PTZ). The p-values ####p < 0.0001, ###p < 0.001, ##p < 0.01 and #p < 0.05 was regarded as statistically significant for the per se groups compared to the control.
FIGURE 3

Gene expression levels for the following genes: (A) CREB, (B) NPY, and (C) HMGB1. The p-values ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05 were regarded as statistically significant for the treatment groups compared to the negative control (LPS + PTZ). The p-values ####p < 0.0001, ###p < 0.001, ##p < 0.01 and #p < 0.05 was regarded as statistically significant for the per se groups compared to the control.
FIGURE 4

Gene expression levels for the following inflammatory genes: (A) TNFα, (B) NFKB, and (C) IL1. The p-values ****p < 0.0001, ***p < 0.001, **p < 0.01, and *p < 0.05 were regarded as statistically significant for the treatment groups compared to the negative control (LPS + PTZ). The p-values ####p < 0.0001, ###p < 0.001, ##p < 0.01 and #p < 0.05 was regarded as statistically significant for the per se groups compared to the control.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Pharmacol
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