A: Images of intersomitic vessels (ISV) in transgenic fluorescent zebrafish (Tg(vegfr2:GFP)) treated with PTK787 and different concentrations (1.25, 2.5, 5, 10, and 20 μM) of 5, using Danhong injection as a positive control. B: Quantitative analysis of the length of ISV in zebrafish treated with 5. Data represented as mean ± SD. ## P < 0.01 compared to the control group; ** P < 0.01 compared to the PTK787-induced group.

Acknowledgments
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