Figure 1

Schematic representation of molecular pathways involved in retinal neuron regeneration from endogenous neural stem cells.

Known positive and negative regulations are indicated. miR-9 links orange and purple transcriptional cascades via the direct inhibition of Lin-28 mRNA binding protein and Tlx/Onecut transcription factors expression. Atoh7: Atonal homolog 7; Sox2: sex determining region Y-box 2; Ascl1a: achaete-scute homolog 1a; miR-9: microRNA-9; Tlx: tailless box vertebrate homologue.
Acknowledgments
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