FIGURE SUMMARY
Title

Early evolution of conserved regulatory sequences associated with development in vertebrates

Authors
McEwen, G.K., Goode, D.K., Parker, H.J., Woolfe, A., Callaway, H., and Elgar, G.
Source
Full text @ PLoS Genet.

Up-regulation of GFP by lamprey and human derived CNEs.

Images of live zebrafish embryos 48–54 hpf (A–C) and 24–30 hpf (D), lateral views, anterior to left. Images are shown as GFP fluorescent (A,B,D) and (C) merged fluorescent and bright field views. (A,C) GFP expression in the hindbrain, driven by an EBF3 CNE derived from lamprey and human respectively. (B,D) GFP expression in the spinal cord driven by a PAX2 CNE derived from lamprey and human respectively. e, eye; hb, hindbrain; mb, midbrain; nc, notochord; ov, otic vesicle; sc, spinal cord; y, yolk. Scale bars represent 100 μm.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.