ZFIN ID: ZDB-PERS-110531-2
Saxena, Meera T.
Email: meera@luminomics.com
URL:
Affiliation: Mumm Lab
Luminomics Inc
Address: Luminomics Inc 1120 15th Street CA-2105 Augusta, GA 30912 USA
Country: United States
Phone:
Fax:
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Emmerich, K., Walker, S.L., Wang, G., White, D.T., Ceisel, A., Wang, F., Teng, Y., Chunawala, Z., Graziano, G., Nimmagadda, S., Saxena, M.T., Qian, J., Mumm, J.S. (2023) Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses. PLoS Genetics. 19:e1010905e1010905
Emmerich, K., White, D.T., Kambhampati, S.P., Casado, G.L., Fu, T.M., Chunawala, Z., Sahoo, A., Nimmagadda, S., Krishnan, N., Saxena, M.T., Walker, S.L., Betzig, E., Kannan, R.M., Mumm, J.S. (2023) Nanoparticle-based targeting of microglia improves the neural regeneration enhancing effects of immunosuppression in the zebrafish retina. Communications biology. 6:534534
Sharrock, A.V., Mulligan, T.S., Hall, K.R., Williams, E.M., White, D.T., Zhang, L., Emmerich, K., Matthews, F., Nimmagadda, S., Washington, S., Le, K.D., Meir-Levi, D., Cox, O.L., Saxena, M.T., Calof, A.L., Lopez-Burks, M.E., Lander, A.D., Ding, D., Ji, H., Ackerley, D.F., Mumm, J.S. (2022) NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation. Nature Methods. 19:205-215
White, D.T., Saxena, M.T., Mumm, J.S. (2019) Let's get small (and smaller): Combining zebrafish and nanomedicine to advance neuroregenerative therapeutics. Advanced drug delivery reviews. 148:344-359
Unal Eroglu, A., Mulligan, T.S., Zhang, L., White, D.T., Sengupta, S., Nie, C., Lu, N.Y., Qian, J., Xu, L., Pei, W., Burgess, S.M., Saxena, M.T., Mumm, J.S. (2018) Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration. Frontiers in cell and developmental biology. 6:88
White, D.T., Sengupta, S., Saxena, M.T., Xu, Q., Hanes, J., Ding, D., Ji, H., Mumm, J.S. (2017) Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina. Proceedings of the National Academy of Sciences of the United States of America. 114(18):E3719-E3728
Mathias, J.R., Zhang, Z., Saxena, M.T., and Mumm, J.S. (2014) Enhanced Cell-Specific Ablation in Zebrafish Using a Triple Mutant of Escherichia Coli Nitroreductase. Zebrafish. 11(2):85-97
Xie, X., Mathias, J.R., Smith, M.A., Walker, S.L., Teng, Y., Distel, M., Koster, R.W., Sirotkin, H.I., Saxena, M.T., and Mumm, J.S. (2012) Silencer-delimited transgenesis: NRSE/RE1 sequences promote neural-specific transgene expression in a NRSF/REST-dependent manner. BMC Biology. 10:93
Walker, S.L., Ariga, J., Mathias, J.R., Coothankandaswamy, V., Xie, X., Distel, M., Köster, R.W., Parsons, M.J., Bhalla, K.N., Saxena, M.T., and Mumm, J.S. (2012) Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish. PLoS One. 7(1):e29916
Teng, Y., Xie, X., Walker, S., Saxena, M., Kozlowski, D.J., Mumm, J.S., and Cowell, J.K. (2011) Loss of Zebrafish lgi1b Leads to Hydrocephalus and Sensitization to Pentylenetetrazol Induced Seizure-Like Behavior. PLoS One. 6(9):e24596

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