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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-000628-4
Huang, Haigen
Email: HAIGENH@UCLA.EDU
URL:
Affiliation: Shuo Lin Lab
Address: Dept. of Molecular,Cell and Developmental Biology University of California 4315 Life Sciences Building 621 Charles E. Young Drive Los Angeles, CA 90095 USA
Country:
Phone: (310) 267-4972
Fax: (310) 206-3987
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Pei, W., Xu, L., Huang, S.C., Pettie, K., Idol, J., Rissone, A., Jimenez, E., Sinclair, J.W., Slevin, C., Varshney, G.K., Jones, M., Carrington, B., Bishop, K., Huang, H., Sood, R., Lin, S., Burgess, S.M. (2018) Guided genetic screen to identify genes essential in the regeneration of hair cells and other tissues. NPJ Regenerative medicine. 3:11
Zhang, Y., Qin, W., Lu, X., Xu, J., Huang, H., Bai, H., Li, S., Lin, S. (2017) Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system. Nature communications. 8:118
Zhang, Y., Huang, H., Zhao, G., Yokoyama, T., Vega, H., Huang, Y., Sood, R., Bishop, K., Maduro, V., Accardi, J., Toro, C., Boerkoel, C.F., Lyons, K., Gahl, W.A., Duan, X., Malicdan, M.C., Lin, S. (2017) ATP6V1H Deficiency Impairs Bone Development through Activation of MMP9 and MMP13. PLoS Genetics. 13:e1006481
Zhang, Y., Huang, H., Zhang, B., Lin, S. (2016) TALEN- and CRISPR-enhanced DNA homologous recombination for gene editing in zebrafish. Methods in cell biology. 135:107-20
Zhao, H., Huang, H., Lin, S. (2016) Chemical approaches to angiogenesis in development and regeneration. Methods in cell biology. 134:369-76
Ear, J., Huang, H., Wilson, T., Tehrani, Z., Lindgren, A., Sung, V., Laadem, A., Daniel, T.O., Chopra, R., Lin, S. (2015) RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood. 126(7):880-90
Marchegiani, S., Davis, T., Tessadori, F., van Haaften, G., Brancati, F., Hoischen, A., Huang, H., Valkanas, E., Pusey, B., Schanze, D., Venselaar, H., Vulto-van Silfhout, A.T., Wolfe, L.A., Tifft, C.J., Zerfas, P.M., Zambruno, G., Kariminejad, A., Sabbagh-Kermani, F., Lee, J., Tsokos, M.G., Lee, C.R., Ferraz, V., da Silva, E.M., Stevens, C.A., Roche, N., Bartsch, O., Farndon, P., Bermejo-Sanchez, E., Brooks, B.P., Maduro, V., Dallapiccola, B., Ramos, F.J., Chung, H.B., Le Caignec, C., Martins, F., Jacyk, W.K., Mazzanti, L., Brunner, H.G., Bakkers, J., Lin, S., Malicdan, M.C., Boerkoel, C.F., Gahl, W.A., de Vries, B.B., van Haelst, M.M., Zenker, M., Markello, T.C. (2015) Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes. American journal of human genetics. 97(1):99-110
Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
Veldman, M.B., Zhao, C., Gomez, G.A., Lindgren, A.G., Huang, H., Yang, H., Yao, S., Martin, B.L., Kimelman, D., and Lin, S. (2013) Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor etv2. PLoS Biology. 11(6):e1001590
Huang, H., Lindgren, A., Wu, X., Liu, N.A., and Lin, S. (2012) High-throughput screening for bioactive molecules using primary cell culture of transgenic zebrafish embryos. Cell Reports. 2(3):695-704
Zhong, H., Wang, D., Wang, N., Rios, Y., Huang, H., Li, S., Wu, X., and Lin, S. (2011) Combinatory action of VEGFR2 and MAP kinase pathways maintains endothelial-cell integrity. Cell Research. 21(7):1080-7
Zhong, H., Zou, H., Semenov, M.V., Moshinsky, D., He, X., Huang, H., Li, S., Quan, J., Yang, Z., and Lin, S. (2009) Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Molecular Biosystems. 5(11):1356-1360
Zhong, H., Wu, X., Huang, H., Fan, Q., Zhu, Z., and Lin, S. (2006) Vertebrate MAX-1 is required for vascular patterning in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 103(45):16800-16805
Huang, H., Zhang, B., Hartenstein, P.A., Chen, J.N., and Lin, S. (2005) NXT2 is required for embryonic heart development in zebrafish. BMC Developmental Biology. 5(1):7
Ju, B., Huang, H., Lee, K.Y., and Lin, S. (2004) Cloning zebrafish by nuclear transfer. The Zebrafish: Genetics, Genomics and Informatics, 2nd ed., Methods Cell Biol.. 77:403-411
Liu, N.A., Huang, H., Yang, Z., Herzog, W., Hammerschmidt, M., Lin, S., and Melmed, S. (2003) Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Molecular endocrinology (Baltimore, Md.). 17(5):959-966
Lee, K-Y., Huang, H., Ju, B., Yang, Z., and Lin, S. (2002) Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat. Biotechnol.. 20(8):795-799
Shafizadeh, E., Huang, H., and Lin, S. (2002) Transgenic zebrafish expressing green fluorescent protein. Methods in molecular biology (Clifton, N.J.). 183:225-233
Huang, H., Liu, N., and Lin, S. (2001) Pdx-1 knockdown reduces insulin promoter activity in zebrafish. Genesis (New York, N.Y. : 2000). 30(3):134-136
Wang, G., Huang, H., Dai, R., Lee, K.Y., Lin, S., and Mivechi, N.F. (2001) Suppression of heat shock transcription factor HSF1 in zebrafish causes heat-induced apoptosis. Genesis (New York, N.Y. : 2000). 30(3):195-197
Huang, H., Vogel, S.S., Liu, N., Melton, D.A., and Lin, S. (2001) Analysis of pancreatic development in living transgenic zebrafish embryos. Molecular and Cellular Endocrinology. 177(1-2):117-124
Woods, I.G., Kelly, P.D., Chu, F., Ngo-Hazelett, P., Yan, Y.-L., Huang, H., Postlethwait, J.H., and Talbot, W.S. (2000) A comparative map of the zebrafish genome. Genome research. 10(12):1903-1914
Postlethwait, J.H., Woods, I.G., Ngo-Hazelett, P., Yan, Y.-L., Kelly, P.D., Chu, F., Huang, H., Hill-Force, A., and Talbot, W.S. (2000) Zebrafish comparative genomics and the origins of vertebrate chromosomes. Genome research. 10(12):1890-1902
Long, Q., Huang, H., Shafizadeh, E., Liu, N., and Lin, S. (2000) Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish. Nature cell biology. 2(8):549-552

NON-ZEBRAFISH PUBLICATIONS