ZFIN ID: ZDB-LAB-180207-1
Zebrafish Core
PI/Director: Paatero, Ilkka
Contact Person: Paatero, Ilkka
Email: ilkka.paatero@utu.fi
Address: Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Tykistökatu 6B, 20520 Turku
Country: Finland
Phone: +358 (0)29 450 3789
Line Designation: tcb


Zebrafish Core provides services such as assistance, expert consulting, training and necessary equipment to perform experiments utilizing zebrafish models. Consulting covers eg. finding and acquiring appropriate fish lines, help in licence applications and experimental design. Established protocols for various zebrafish methods, such as embryo culture, transgenesis, targeted mutagenesis and sample preparation, are available through the Zebrafish Core. Zebrafish Core also arranges training in the scientific use of zebrafish models.


Heliste, J., Jokilammi, A., Vaparanta, K., Paatero, I., Elenius, K. (2021) Combined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia. Scientific Reports. 11:16661
Lee, M., Betz, C., Yin, J., Paatero, I., Schellinx, N., Carte, A.N., Wilson, C.W., Ye, W., Affolter, M., Belting, H.G. (2021) Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip1. Development (Cambridge, England). 148(15):
Al-Akhrass, H., Conway, J.R.W., Poulsen, A.S.A., Paatero, I., Kaivola, J., Padzik, A., Andersen, O.M., Ivaska, J. (2021) A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance. Oncogene. 40(7):1300-1317
Heliste, J., Chheda, H., Paatero, I., Salminen, T.A., Akimov, Y., Paavola, J., Elenius, K., Aittokallio, T. (2019) Genetic and functional implications of an exonic TRIM55 variant in heart failure. Journal of Molecular and Cellular Cardiology. 138:222-233
Sahgal, P., Alanko, J., Icha, J., Paatero, I., Hamidi, H., Arjonen, A., Pietilä, M., Rokka, A., Ivaska, J. (2019) GGA2 and RAB13 promote activity-dependent β1-integrin recycling. Journal of Cell Science. 132(11):
Paatero, I., Veikkolainen, V., Mäenpää, M., Schmelzer, E., Belting, H.G., Pelliniemi, L.J., Elenius, K. (2018) ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos. Molecular biology of the cell. 30(2):209-218
Paatero, I., Alve, S., Gramolelli, S., Ivaska, J., Ojala, P.M. (2018) Zebrafish Embryo Xenograft and Metastasis Assay. Bio-protocol. 8:e3027
Paatero, I., Sauteur, L., Lee, M., Lagendijk, A.K., Heutschi, D., Wiesner, C., Guzmán, C., Bieli, D., Hogan, B.M., Affolter, M., Belting, H.G. (2018) Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin-F-actin based oscillatory cell-cell interaction. Nature communications. 9:3545
Pekkonen, P., Alve, S., Balistreri, G., Gramolelli, S., Tatti-Bugaeva, O., Paatero, I., Niiranen, O., Tuohinto, K., Perälä, N., Taiwo, A., Zinovkina, N., Repo, P., Icay, K., Ivaska, J., Saharinen, P., Hautaniemi, S., Lehti, K., Ojala, P.M. (2018) Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and β1-integrin activation. eLIFE. 7
Jacquemet, G., Paatero, I., Carisey, A.F., Padzik, A., Orange, J.S., Hamidi, H., Ivaska, J. (2017) FiloQuant reveals increased filopodia density during breast cancer progression. The Journal of cell biology. 216:3387-3403