| Phenotype: | negative regulation of gene expression via chromosomal CpG island methylation increased occurrence, abnormal |
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| Note: | This statement combines anatomy and/or ontology terms with phenotype quality terms to create a complete phenotype (EQ) statement. For detailed information on individual terms, click the hyperlinked term name. |
| Name: | negative regulation of gene expression via chromosomal CpG island methylation |
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| Synonyms: | DNA hypermethylation of CG island, DNA hypermethylation of CpG island, epigenetic regulation of gene expression via CpG island hypermethylation, hypermethylation of CpG island, negative regulation of gene expression via chromosomal CG dinucleotide methylation, negative regulation of gene expression via chromosomal CpG dinucleotide methylation, negative regulation of gene expression via chromosomal DNA cytosine methylation, negative regulation of gene expression via CpG island hypermethylation, negative regulation of gene expression via CpG island methylation |
| Definition: | An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide associated with the transcription start site of genes. |
| Ontology: | GO: Biological Process [GO:0044027] QuickGO AmiGO |
| Name: | increased occurrence |
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| Synonyms: | increased incidence |
| Definition: | An occurrence which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0002051] |