base of crypt of Lieberkuhn

Term ID

UBERON:0013739

Synonyms

• basal portion of intestinal gland
• base of intestinal gland
• base part of epithelium of intestinal gland

Definition

The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell. (2)

References

Ontology

Uberon Ontology