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Sequence Ontology

group_I_intron

Term ID
SO:0000587
Synonyms
  • group I intron
Definition
Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00028
References
Ontology
Sequence Ontology
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