raps-insc complex

Term ID

GO:1990499

Synonyms

• partner of inscuteable-inscuteable complex
• Rapsynoid-Inscuteable complex

Definition

Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2). 22171003

References

Ontology

GO: Cellular Component    QuickGO    AmiGO