Bfa1-Bub2 complex

Term ID

GO:1990334

Synonyms

Definition

A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation. 16449187

References

Ontology

GO: Cellular Component    QuickGO    AmiGO