Search Ontology:
GO: Cellular Component

RSP5-BUL ubiquitin ligase complex

Term ID
GO:1990306
Synonyms
  • RSP5-BUL1 complex
  • RSP5-BUL2 complex
Definition
A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation. 9931424
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is a type of
Phenotype
Phenotype caused by Genes
Citations
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