histone H4K20me methyltransferase activity

Term ID

GO:0140941

Synonyms

• histone H4 methyl lysine(20) N-methyltransferase activity (H4-K20 specific)
• histone H4-K20 dimethylation
• histone H4K20 dimethylation
• histone H4K20me methylase activity

Definition

Catalysis of the reaction: N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H+ + N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the monomethlyated lysine residue at position 20 of histone H4, producing H4K20me2.

References

• EC:2.1.1.362
• RHEA:60348

Ontology

GO: Molecular Function    QuickGO    AmiGO