Search Ontology:
GO: Cellular Component

transforming growth factor beta complex

Term ID
GO:0099126
Synonyms
  • TGF-beta complex
  • TGF-beta dimer
  • TGFB complex
  • TGFB dimer
  • TGFbeta complex
  • TGFbeta dimer
Definition
A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerization and dissociation of the LAP. 22943793
References
Ontology
GO: Cellular Component    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes
Citations
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